@feld @kravietz you have set up a binary distinction "happy about 100% of big ag behavior pro GMO" vs "complete moron who doesn't understand basic science anti GMO"

there is a lot of nuance and challenging trade-offs, also big players, subsidies, and potential regulatory capture. TO an extent, technology has unquestionably improved agriculture, and arguably, beyond a point, technology is being used for profits at the expense of ecological and dietary health. the calculus has been based on minimizing human labor and maximizing profits via useage of subsidized fossil fuel. One specific vision of the economy.

Yes, there is the farming 1e9 acres with mostly automated mega-machines and a few decorative human operators. There is also Curtis Stone and JM Fortier making 6 figures on less than an acre. If you decide one thing is the answer and subsidize it, you've made your own conclusion instead of letting the market decide.

@hushroom @feld

Farming subsidies etc are the reality in high-income countries like UE or USA. But UE doesn't really *need* GMO because it can produce huge amounts of cheap food already.

GMO is needed in the first place by low-income countries in Africa and Asia, which still experience famines or vitamin deficits in 21st century! And here you have Greenpeace "heroically" destroying Golden Rice or Bt brinjal crops for the sake of... "purity" and fanatics like Vandana Shiva.

@kravietz @feld Food production systems are made up from so many variables. If you come to the conclusion that one needs "GMO" seeds, you have made many assumptions about a food system already.
And the OP of this thread imo just doesn't understand that the term GMO is commonly used to refer to certain advanced gene editting techniques bypassing the typical plant reproductive cycles, requiring a laboratory and done for the first time in the 1990s, as a distinct technique within the more general category of "intentional breeding" that has been going on for thousands of years.
By ignoring the common use of GMO and parsing each word individually, you can argue that GMO is the whole broad category JUST so you can make fun of people based on a technicality of your own definition?

Its like how a bunch of studies, data, and models were combined about climate, atmosphere, themodynamics, industry, population growth, etc were used to make some alarming projections, and they called the overall concept "Global Warming" and despite predicting more extreme weather events including winter storms, it gets constantly "disproved" by people who think "Global Warming" literally just means global warming.

@hushroom @feld

> so you can make fun of people based on a technicality

Sorry, I'm honestly trying but I don't understand what is your argument here?

@kravietz The OP of this thread, a picture of "NO GMO" on brocolli, I think refers to the common meaning of GMO. But feld makes the argument GMO = everything to do with entire history of selective breeding etc, therefore all broccoli crops and dogs breeds are GMO.

Its fine if you want define GMO like this, but then provide another term for specifically laboratory gene splicing from different species or synthesized genes.

I'm not saying all of the concerns are justified, but there are SOME concerns that apply to GMO, and its inaccurate to write them off as "we've literally been doing this for thousands of years".

@hushroom

Obviously, a mutagen is like a bulldozer - it can modify a dozen of genes. Can make the plant more sweet, or more poisonous. But we don't care as long as the result is sweeter or bigger or whatever we like.

Then we discovered gamma rays, which do the gene splicing even better. New varieties of tomatoes, apples, potatoes, wheat etc etc. All produced through 20th century using mutation breeding.

@kravietz I do know of mutation breeding as a thing, and responsible for a few well known traits, but I have never found any information that mutation-induced genes are present in all or most crops.

@hushroom

Actually, Non-GMO Project maintains a whole list of plants that are "high risk" of being modified using CRiSPR (which they call GMO). The funniest part however that for many plants they *cannot* in any way distinguish them from non-CRiSPR (non-GMO as they call it) plants, yet they speak of "risk" and "contamination".

nongmoproject.org/gmo-facts/hi

@kravietz Ok, I'm not going to defend any Greenpiece tier nonsense you pull up, just like I won't assume you believe every Monsanto PR i can dig up.

Here's a simple question to illustrate my point, if you have a "peanut allergy" you have an allergy to a compound produced by all or most species of peanut cultivated. There is no gene that makes any tomato, or tomato compatible plant produce this compound. No matter what a classical plant breeder does with tomatoes, you can assume its safe for anyone with a peanut allergy to eat them. Put CRISPR on the table and this isn't a safe assumption anymore. Again, I'm not saying to march in the streets, just that this is distinct, new technology (even if its to pursue a long time goal) that does have some unique concerns to its predecessor techniques.

@hushroom

Check this book -

libgen.lc/ads.php?md5=3816FB87

chapter 5 "Green Genes" as it goes into great detail about genetic engineering techniques, including origins of opposition, and including peanut allergies (screenshot). It was written by a recognized environmentalist Stewart Brand who condemned WWF, FoE and Greenpeace on their anti-scientific position, as many other environmentalists did.

@kravietz Thanks! just finished chapter 5 and 6, I think I'll read through this whole book. I know of Stewart Brand from "whole earth catalog"so this book is very interesting coming from someone i considered to be "environmentalist".

overall I thought it was a good explanation of the science, including even admitting some of GE's shortcomings/limitations in regards to Africa: it doesn't help depleted soil, doesn't fix lack of access to irrigation or fertilizer.

The author dispels some fears about Monsanto monopoly by listing a handful of other potential competitors: syngenta, dupont, dow. Most of these companies have merged or been acquired, and look at ownership of the largest producer of vegetable seeds: https://en.wikipedia.org/wiki/Seminis

I think this centralization is whats concerning, not GMO technology. Another thing that book implied is that we'd be seeing a proliferation, or cornucopia, of biofortified GM crops being developed and freed from patents as Golden Rice and GE Corn. The book predicted the technological capability would proliferate, in fact it has centralized.

That book did highlight many completely absurb criticisms, eg fear of "playing god", that I agree are totally irrelevant and not unique to GMOs.
Follow

@hushroom

So the argument about "GMO market not being successful" is a bit like Greenpeace blocking nuclear plant building and operation by *any* means and then saying "look, it's expensive and delayed" πŸ˜‚

Having said that, many GMO plants like Golden Rice and Bt brinjal *are* available without patents and were developed by public research institutions or NGOs. We just need more public research into this... but public universities are harassed even more!

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@kravietz Yes there are puny underfunded protestors against fortune 500 companies, a bit like a fly vs an elephant. Certainly, there are also technical challenges to this cutting edge research.
Just because you've demonstrated the presence of protestors, you can demonstrate 100% lack of progress to Greenpeace and 0% lack of progress to inherent technical challenges? I don't buy it that easy.

@hushroom

> you've demonstrated the presence of protestors

Development, sales and even research of genetically engineered organisms in many countries, especially EU, is very restricted, and this is specifically as result of Greenpeace lobbying.

How can you make any progress if you can't even legally do research? That's probably the largest absurdity of the "precautionary principle" that they embedded in the EU legal framework to fight GMO.

@kravietz Well you are in the control group, i am in the experimental group, so our perspectives differ. 70% of my diet has GMO ingredients, we publically fund research, development, and deployment. One source of funding is through government subsidies to farmers. subsidy is proportional to acres farmed, bulk of farmland owned by large corporations here, small farms are mostly gone, and their contribution to total food production is extremely marginal.

Also we have publically funded land grant universities all doing this research, i wouldn't be surprised if a lot of the success stories originated from university research. However, by design these universities focus on research not commercialization. So their work gets sold, or spun off into commercial ventures to pursue it.

So why aren't there more and more competitors? Why is every company getting acquired, fewer and fewer companies competing, with more resources each, building a bigger moat against competitors. In my view its a monopoly, same as tech companies have been in the past. Hoping a startup brings competition to the Monsanto conglomerate is like hoping a garage startup displaces (or even competes with) facebook or google.

Maybe this is an American corporate-dominated economy centric view. Maybe Europeans have precedent to be more optimistic in this case?

@hushroom

> American corporate-dominated economy centric view

It indeed is. You probably haven't heard about University of Agricultural Sciences, Dharwad or Tamil Nadu Agricultural University, Coimbatore have you? Neither did I until I read Brand's book.

But it was them who created the Bt brinjal and released it to India and Bangladesh, leading to a 39% reduction in the use of pesticides and 43% increase in yield. Which, by the way, translates to equivalent decrease in land use.

@kravietz Well I at least heard of them since yesterday when I read part of Brand's book you sent in that libgen link (thank you again btw).
I do agree with many of the claims in that book, but to remain critical, why has the list of success stories like bt corn and golden rice not proliferated?
What is the cost to develop one GMO crop? What are the top goals/challenges of agriculture? Are there other areas of research besides GMO with potential benefit, that are unfunded? How are the organizations receiving funding for GMO researching choosing their research goals?

(and to re-iterate, i'm not saying any of these questions I asked are to imply that GMOs are demons and should be banned. just, that in addition to blanket unscientific denial that is dispelled in Brand's book, there *are* some questions that can be asked
involving GMOs and where we're going with them without being thrown into the "scientifically illiterate brainwashed" group.)

@hushroom

> i'm not saying any of these questions I asked

Oh, no - I actually respect your position very much and the fact that you are actually checking the sources and responding to them in informed manner. We are actually discussing, not having two monologues!

You can't imagine how rare this is these days!

@kravietz I know, i am in disbelief we aren't insulting each other :) I'm realizing the climate surrounding this issue is quite different for each of us. I knew that europe banned import of US GMO crops, but i didn't realize how much the sentiment permeated common scientific understanding. I maybe assumed it was more likely an easy excuse to implement a somewhat protectionist policy to strengthen EU farms against US ag industry competition. Aka, I thought Euros thought Americans will be sloppy with the technology, not that that GMO is inherently dangerous.

@hushroom

Yes, it's quite a surprising phenomenon - the first GMO scare came from Jeremy Rifkin (US) and then was imported into EU by Greenpeace, Friends of Earth and WWF. They actually lost many prominent supporters (including Brand) due to their fanatic position.

@hushroom

But what happened next was even more surprising. Right now you've got situation when IARC (an EU agency) produces highly controversial opinions about various things being carcinogenic (e.g. glyphosate).

Then these opinions are used for class lawsuits in the US (!) to win massive amounts of money from US companies. The law companies then employ IARC people as consultants, they write more opinions etc etc.

european-seed.com/2019/04/amer

@hushroom

Just to be clear: I'm absolutely for suing companies like DuPont for what they did with PFOA in the US - unfortunately, some cases that look like that one, aren't.

en.wikipedia.org/wiki/Perfluor

@kravietz It seems the cases where there is clearly wrongdoing, the guilty so rarely pay for their mistakes. DuPont is also no more, its another company also with the name of DuPont, created in the 3 way spinoff of another company called DowDuPont.

Just like Union Carbide no longer "exists" so it can't have responsibility for https://en.wikipedia.org/wiki/Bhopal_disaster

Its not black and white, good and evil, because despite slimy behavior these chemical companies do also manufacture the foundation of most infrastructure and technology.
@kravietz Also, I didn't realize how extensive libgen was. I found a book I read recently that discusses this topic and improved my understanding of the topic somewhat. https://libgen.lc/ads.php?md5=45c871cf6fb27abca6b1b98b8c41feb9

The book is only tangentially related to our discussion, so just see Ch 22 which focuses on this issue. Don't expected any bombastic "This will DESTROY GMO" claims. In fact, the author does explain the unique problems that only GMO can solve, some areas where GMO may offer a solution, and also cases where GMO is not an appropriate tool. It doesn't discredit anything in the Brand's book, but it just clarifies the whole process including research beforehand - to determine what gene to put where to do what - and field trials and growouts of seedstock afterwards, in addition to the actual laboratory component. While the chapter ends with what sound like critical comments on GMO, I would argue it's critical of *how GMO is currently being used* but is still in support of the science and its potentials.

@hushroom

> a startup brings competition to the Monsanto

This is actually incorrect. There's a thriving independent community of independent biotechnology researchers - individuals, small companies etc, all around the world. You can find tons of them on indiebio.co/

@kravietz Sorry, can you send me a list of some varieties these companies have released then?
Surely, its as easy as pick a vitamin, pick a crop, insert the gene, then just start propagating to grow enough to sell? With 1.1 billion i'm sure they've produced a lot, or are going to?

But once they do, what stops them from being acquired Monsanto? Payday for them, payday for investors, best quality labs in the world for researchers. Are these guys pledged to release their work somehow?

Do you think ycombinator is an attack on facebook or google? independent software consultants and google are both tech companies, but that doesn't mean they are competiting.

@hushroom

> Monsanto

There's no such company as Monsanto by the way. It has been acquired by Bayer.

@kravietz Thats why the word before and after "Monsanto" were "The" and "Conglomerate", because I can't keep up with how fast Dow and Dupont and Monsanto and Syngenta and ChemChina & the rest are acquiring, merging, etc.

None of my points are meant to be specific brand, CEO, or company. more general to any agtech(or ag-pharma-chem-tech) company big enough to be in the fortune 500.

Its like solving the Microsoft monopoly by selling Microsoft to Google.

@hushroom

> can you send me a list of some varieties

No, I cannot. I find it quite arrogant of people to ask "can you show me" in a debate if they can easily check for themselves and my experience indicates this is a simple blame-shifting technique to justify their own beliefs and bias. And when presented with data they just ignore it or dismiss further escalating demands.

@kravietz Golden Rice is a pointless PR tactic. People in rice-growing areas never used to suffer from vitamin deficiency. Until industrial ag champions came along and told them it was a great idea to grow rice in monocultures, instead of using polycultures that provided them with a range of foods, covering all their nutrient needs. The solution malnutrition is mixed farming, controlled by communities, not GMOs from the Great White Saviour.

@hushroom

@strypey @hushroom

Yes, that's a well known tune in some environmental circles: move THEM back to jungle where they can live at pre-industrial mortality levels as WE live in developed countries and send our precious WHITE kids to schools.

Kill two birds with one stone: prevent progress, and at the same time stop overpopulation by letting them die in the bushes where WE don't see them.

@strypey @hushroom

Sorry, I was born in 80's Eastern Europe and I can tell you one thing: nobody there wanted to live like our grandparents, who worked 16h per day to feed themselves in old-style farming and died at age of 50.

Everybody wants to live like Vandana Shiva, who lives in Delhi, charges $40k per speech at events where she flies in business class to teach how the poor people should be living in the jungle farming polycultures...

@strypey @hushroom

A case study - I can guarantee, that if we in Eastern Europe did not already transform farming during communism (mostly in 60's after fall of Lysenkoism), we would with no hesitation clone, steal and do everything else necessary to obtain the seeds as farmers in India and Bangladesh are doing now. And then prevent Greenpeace activists from destroying it with any means necessary.

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